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CrossRef 11,243 View 257 Download 17 Web of Science Crossref Original Articles Steatotic liver disease TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD Baokai Sun, Xiaoqian Ding, Jie Tan, Jie Zhang, Xueru Chu, Shuimi Zhang, Shousheng Liu, Zhenzhen Zhao, Shiying Xuan, Yongning Xin, Likun Zhuang Clin Mol Hepatol 2024;30(4):863-882
In a dysregulated system, it tends to promote regulation
In addition, the activated UPR and hence the increased ERS further exacerbates inflammation and hinders protective processes like mTORc activation and autophagy (84)