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Integrating these research results, GPX4 can be regarded not only as a potential biomarker sensitively reflecting OA pathological severity and disease stage but also as a therapeutically promising target with core protective functions in OA progression

Thus, the p53 signalling pathway in adipocytes might represent an interesting target to ameliorate the effectiveness of dietary weight loss interventions

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The most recent report that we have is that 1 in 8 adults has taken an obesity management medication. OMMs are most effective for long-term weight loss when paired with behavioral changes, such as eating more fruits and vegetables, Pratt said