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But research suggests that hypoglycemia is underreported in older adults because symptoms like confusion and fatigue are nonspecific or misinterpreted as dementia-related

Studies show that higher IGF-1 bioavailability, measured by the IGF-1 to IGFBP3 ratio, is associated with lower perceived age and reduced skin wrinkling

Between group differences in secondary and exploratory outcomes will be assessed using regression models as appropriate to the response outcome distribution using baseline values of the respective outcomes as adjustment covariates