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Retatrutide drives the caloric deficit through profound appetite suppression and increased energy expenditure

This is consistent with the mechanistic hypothesis that semaglutide, through its GLP-1 receptor-mediated effects, protects pancreatic -cell function and improves glucose tolerance by regulating insulin secretion 34

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In the CY 2023 OPPS/ASC final rule with comment period (87 FR 71863 through 71864), we assigned the newly established CPT codes 36836 and 36837 to APC 5194 based on our assessment of the CY 2023 geometric mean cost of predecessor codes HCPCS codes G2170 ($12,055.90) and G2171 ($13,486.08) and their APC assignment