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These findings suggest that the mitophagy induced by KU-57788 may be a stress response to mitochondrial damage, rather than a direct mechanism contributing to its anti-ATC activity

Shindo N, Fujisawa T, Sugimoto K, Nojima K, Oze-Fukai A, Yoshikawa Y, Wang X, Yasuda O, Ikegami H, Rakugi H (2010) Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model