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In a ventilation-induced lung injury (VILI) model, pretreatment with CMT-3 decreased neutrophil infiltration and myeloperoxidase levels, which correlated significantly with MMP-9 activity

The results demonstrated that there is a strong direct correlation between baseline A1c level and the magnitude of the decrease in fasting glucose and A1c induced by these drugs (i.e., significantly greater reductions in both fasting plasma glucose and A1c were observed in groups with higher baseline A1c levels)

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