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showed that NAC (6001,000 mg/day) restored antioxidant balance and reduced inflammation, though without lung function improvement ( A phase II trial using high-dose NAC (2,800 mg/day, 12 weeks) increased sputum glutathione but did not affect inflammatory markers or lung function ( 1 decline (by 150 mL) versus placebo over 24 weeks, though primary endpoints were unmet due to underpowering ( Cystic fibrosis patients with chronic P

We found a notable decrease (less than 0.2) in the peak intensity at the N-terminus and helices 3 and 4 of the FOXO4 FHD (Figure