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Recent data suggest that SAM coordinately regulates homocysteine remethylation and catabolism by inhibiting methionine-conserving enzymes with low K m values and activating methionine-catabolizing enzymes with higher K m values (Finkelstein, 1990

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Individual records included age, gender and year of the patient's first specialized evaluation or, if there was no patient follow-up, when the sample had been obtained, HCV genotype, probable route of infection, polymorphism rs12979860, native vs immigrant status, geographical area of origin and HIV coinfection

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