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All but one study lacked clear and statistically significant evidence of self-reported respiratory diagnoses associated with EC use among PWNS, or showed a tenuous association with mild respiratory symptoms

Even mellow strains can slow reaction time or cloud decision-making

An MRTP does

Smoking can aggravate or initiate: Chilblains Frostbite Primary or secondary vasospastic disease (Raynaud phenomenon) Ulceration, in patients with systemic sclerosis Thromboangiitis obliterans (Buerger disease), in which blood clots occur in small blood vessels Cholesterol emboli associated with atherosclerosis Thrombosis caused by thrombophilia, antiphospholipid syndrome or drugs including oral contraceptives