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Among those tested, Cur10 demonstrated the strongest binding, exhibiting the lowest IC 50 value of 9.64 M, while Cur07 and Cur06 showed IC 50 values of 19.86 M and 20.79 M, respectively (467)

Fourth, in the complex pathophysiology of the ICU setting, particularly in sepsis, multiple regulated cell death (RCD) pathways including apoptosis, pyroptosis, necroptosis, and ferroptosis, contribute to tissue injury and organ failure, but they do not operate in isolation

In view of the very poor cure rate with standard excision, some surgeons combine the two methods: surgical excision of the lesion, then three months treatment of the area with imiquimod cream

International Journal of Molecular Sciences , 2024 , 25 (12), 6345