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The FAERS remains pivotal for post-marketing pharmacovigilance, yet its dependence on spontaneous reports introduces critical methodological constraints

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Notably, a recent in vitro study reported that application of porcine-derived collagen peptides increased integrin 21 expression in keratinocytes and dermal fibroblasts and activated an ERKFAK signaling cascade during wound closure, suggesting that collagen peptides may influence integrin-related processes relevant to matrix remodeling and repair [49]

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