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They also found the semaglutide group had a decreased risk for death from any cause, death from cardiovascular causes, and the measured heart failure composite, which included having an urgent medical visit or hospitalization from heart failure and death from cardiovascular causes

Placebo: Participants in both trials typically lost less than 3% of their body weight

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Wegovy (subcutaneous semaglutide 2.4 mg) is approved for reducing major adverse cardiovascular events in adults with established cardiovascular disease and obesity or overweightthe first weight-management medication to receive this indication