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Buchanan and colleagues reviewed the limited available preclinical and clinical data and concluded that E-cigarette use is associated with inflammation, oxidative stress, and haemodynamic imbalance leading to increased cardiovascular disease risk. Current evidence is available primarily from acute studies and the effects of chronic exposure remain an urgent research question

Nicotine is the ingredient that makes e-liquids such an effective substitute for smoking, as vapers can satisfy their cravings without consuming all the harmful chemicals contained in rolling tobacco or cigarettes

A survey of conventional cigarette smokers experiences with e-cigarettes

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