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Notably, administration of GEP44 resulted in an 80% reduction in food intake and a more profound loss of body weight than what could be achieved in response to treatment with several of the US Food and Drug Administration (FDA)-approved GLP-1RAs, including Ex-4 and liraglutide (LIRA)

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(The Washington Post notes that some Part D plans do cover Wegovy if prescribed for reducing cardiovascular risk, or Zepbound for obstructive sleep apnea, but not for obesity ( [38] ) ( [39] ).) In summary, nearly all current GLP-1 weight-loss usage depends on commercial/employer coverage , which is highly variable and restrictive