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544 articles screened, 36 included (35 preclinical, 1 clinical): PMC12313605 2025 narrative review Katzman BM et al

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In line with these observations, the nitrotyrosine level in the liver of hepsin / mice was approximately 2- to threefold higher than that measured for wild-type mice, with this difference becoming noticeable as early as 2 h post-APAP administration (Fig