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Acetaminophen (Paracetamol) : This common painkiller may interact with glutathione, especially in high doses, which could result in liver damage

Large amounts of pantothenic acid can cause diarrhea

Overall, these data suggest that NR4a1 overexpression alone does not exacerbate TAC-induced pathological cardiac remodeling but counteracts the therapeutic effect of Sema, further confirming that NR4a1 is a target of Sema in pressure overload-induced cardiac remodeling and dysfunction