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Since the activity of CYP1A2 varies greatly from individual to individual, literature evidenced that there are different influential factors, such as genetics, coffee consumption, oral contraceptive use and smoking, even if the mechanisms are complex and not completely clear [21]

The proposed bill, introduced Monday, would make it illegal to sell tobacco products to anyone under the age of 21

1 Despite their shared characteristics, each disorder has distinct clinical manifestations and pathological profiles