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Consequently, the composition of an individuals microbiota is shaped by factors such as age, sex, ethnicity, and geographical region, resulting in a uniquely personalized GI microbial ecosystem (212)

GLP-1 agonists can support these efforts by helping to control appetite and making it easier to stick to a healthy eating plan, but they should not be relied upon as the sole strategy for weight management

PMID 1313797 Gke R et al

Weight Loss Results: What the Data Shows When it comes to shedding pounds, injectable GLP-1s deliver superior results based on extensive clinical trials: Injectable semaglutide (Wegovy ) : 15-17% average body weight loss Injectable tirzepatide (Mounjaro /Zepboun d) : Up to 22.5% average body weight loss FDA-approved oral semaglutide: 13.6-16.6% average body weight loss Compounded ODT formulations : No published clinical trial data available A real-world comparison study found that patients on injectable semaglutide lost 1.62kg more than those on FDA-approved oral semaglutide over 26 weeks, which was not significant