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FIGURE 2 3.2 Impact of linezolid and/or vitamin C on antioxidant and oxidative stress parameters As shown in Figure 3, the treatment with linezolid induced a status of oxidative stress represented by significantly (p 0.05) elevated levels of hepatic and renal NO (76.23 1.677 mole/g and 95.88 1.065 mol/g tissue, respectively) versus 44.42 1.054 mole/g and 55.31 1.56 mole/g tissue, respectively and lipid peroxidation product, MDA, (65.22 1.116 and 69.51 0.85 nmol/g tissue, respectively) versus 32.76 0.745 nmole/g and 39.15 0.914 nmol/g tissue, respectively

Antioxidants or inhibition of ferroptosis with iron chelators may prevent and treat testicular diseases because inhibition of ferroptosis has been shown to significantly improve male reproductive function in various animal models

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Statistical analysis Statistical analysis of data was performed using the GraphPad Prism 8.3 software