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After that, Centers for Medicare & Medicaid Services will evaluate outcomes and make a decision on extending coverage
Many of these trials are extending the duration of treatment beyond initial feasibility studies, sometimes lasting 30 to 36 weeks, to evaluate sustained effects
Patients who were on semaglutide 2.4 mg for a year or more may tolerate escalation comfortably because their gut has adapted to GLP-1 receptor activation, but re-starting at 2.5 mg remains the safer approach
Genetic context adds a different dimension, mapping the metabolic terrain a GLP-1 protocol acts on before you subscribe anywhere
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