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This is the opposite of the antagonistic relationship seen with ibuprofen

After starvation for 6 h, the cells were left untreated or stimulated with 0.2 nM human recombinant EGF in the presence or absence of the indicated concentrations of gefitinib or aML5-PEG3 for 5 min

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Proteomic studies have repeatedly shown that the cysteine residues of cytoplasmic proteins are oxidized inside cells that are exposed to exogenous H 2 O 2 , and those data have been cited to support the notion that protein thiols are modified during oxidative stress ( 2 O 2 concentrations in the millimolar rangefar in excess of the sub-micromolar concentrations that pertain to model bacteria ( In this study we measured the abilities of different oxygen species to oxidize either model thiols or protein cysteine residues in vitro