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In addition, those who have COMT Val/Val genotype (genotype with greater enzyme expression) were associated with a significantly increased risk of UF as compared to those with Val/Met genotype (intermediate expression) and Met/Met genotype (low expression), which could have explained the higher risk of UF in African American women (47% having Val/Val genotype) (Al-Hendy and Salama, 2006)

Maintenance After the initial boost, many people transition to a maintenance schedule

Methodological heterogeneity across studies using IHC, Western blot, or qPCR can also yield variable Bax/NF-B profiles, with in vivo IHC particularly sensitive to immune cell recruitment

PMID: 28041678