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again, oxidative stress is believed to be the culprit, with decreased GSTO gene expression resulting in a lowered age of onset for the diseases

Eligibility for GLP-1 RA therapy for weight management was defined as: (1) BMI 30 kg/m 2 , or (2) BMI 2729.9 kg/m 2 with at least one documented weight-related comorbidity (arterial hypertension, coronary artery disease, hypercholesterolemia, or sleep apnea)