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The exact mechanism of ferroptosis in OA, coupled with discovery of possible targets in the ferroptosis pathway, is essential to improve therapeutic approaches for persons suffering from OA

Understanding this fundamental property helps explain why certain populationssuch as vegans, older adults, and those with gastrointestinal conditionsmay require supplementation despite the body's storage capabilities

Plant-derived phytochemicals show strong chemopreventive activity against breast cancer by selectively modulating important signaling pathways and offering a safer profile than many conventional treatments ( Figure 3 )

2017;26(2):343352.e2