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Vaping among youth who have never smoked may be especially concerning as nicotine addiction established at this life-stage could be long-lasting, potentially increasing the likelihood of cigarette use over the life-course and/or risk for psychiatric disorders, future substance use and poor later life cognition [2, 29,30,31]

The common side effects are weight gain, dyslipidemia, increased adiposity, elevated body mass index, increased insulin resistance, and metabolic alterations

Cue reactivity in non-daily smokers