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These problems are typically associated with poor-quality supplements containing impurities rather than pure glutathione

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6 Reduced levels of B12 and folate compromise the bodys ability to convert homocysteine to methionine, leading to elevated homocysteine

The major hurdleslack of objective diagnostic biomarkers, the BBB impeding drug delivery, significant patient heterogeneity, and the need for more sensitive clinical trial endpointscollectively form a critical barrier to progress