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These researchers combed through a trove of internal tobacco industry documents to reveal how companies manipulated menthol levels in cigarettes and introduced new menthol brands to gain market share, particularly among adolescents and young adults. They brought younger customers in with light menthol flavor, and devised more heavily mentholated brands for older smokers who wanted a stronger taste

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Nicotine stimulates the expression of cFos protein in the parvocellular paraventricular nucleus and brainstem catecholaminergic regions

This trend has had a particular impact on the male population, where smoking prevalence continued to decline, especially after 1975, when increased awareness of smoking cessation led to a significant reduction in male smoking prevalence