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Given the essential role of astrocytes in clearing and detoxifying many substances and the changes in astrocyte functions that such substances can evoke, it is interesting to consider (and worthy of more extensive investigation) that chronic exposure to trace amounts of such substances might act as risk factors and comorbidities in a variety of CNS neurodegenerative conditions

Slow growing colonies were patched onto YPD agar plates with and without nourseothricin (200 g mL 1 ) to screen for nourseothricin-sensitive colonies

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