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Metformin typically lowers A1C by 1.02.0%, while semaglutide achieves reductions of 1.52.5%, and the weight loss gap widens dramatically: metformin produces 23 pounds of loss versus semaglutide's 1522 pounds over comparable time periods

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We continue to evaluate future development options for retatrutide, but have not announced development plans for these types of indications at this point in time." "Retatrutide is an investigational molecule that Lilly is studying for the treatment of obesity, obstructive sleep apnea (OSA), knee osteoarthritis and type 2 diabetes

Most users report minimal ongoing side effects after reaching maintenance dose