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Therefore, the 2022 KDIGO guidelines recommend long-acting GLP-1 RAs with established cardiovascular (CV) benefits as the preferred second-line therapy for glycemic control and CV risk reduction in adults with type 2 diabetes with established cardiovascular disease (CVD) or a high CV risk profile

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Individuals with obesity should be counselled to accumulate at least 150 minutes a week of moderate aerobic exercise, such as walking, and to engage in resistance training to preserve lean mass