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High-dose oral supplementation may be another treatment option, because consuming 1,000 g (1 mg) per day of vitamin B 12 orally should result in the absorption of about 10 g/day (1% of dose) by passive diffusion
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subcutaneous produces reliable systemic absorption Requires greater technique and carries a marginally higher risk of injection site reaction Who injection is best suited for: Tendon, ligament, or muscle injuries Post-surgical tissue recovery Bone healing support Systemic anti-inflammatory goals Any indication where the target tissue is not the GI tract Practical considerations: Requires comfort with self-injection or clinical administration Sterile preparation is non-negotiable contaminated peptide solutions carry real infection risk Quality of the compound matters enormously
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