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The studies showed that treatment reduced body weight gain by over 50% compared to controls over a 19-day period, with increased lipolytic activity specifically in adipose tissue deposits

Each film-coated tablet of JANUVIA contains 32.13, 64.25, or 128.5 mg of sitagliptin phosphate monohydrate, which is equivalent to 25, 50, or 100 mg, respectively, of free base and the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, sodium stearyl fumarate, and propyl gallate

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Moreover, the liver produces many hormones and growth factors that influence cardiovascular function