Given the promise of GLP-1 RA in the risk reduction of AMD and other ocular diseases, prospective trials should be considered to better characterize the potential protective effects of this medication class against ocular disease, they concluded
Obesity significantly raises the risk of heart disease, diabetes, certain cancers, and premature death
Peripheral anorexigenic mechanisms The postprandial satiety has been ascribed to numerous signaling molecules, expressed and released in the gastrointestinal tract and also in hypothalamic ARC, to inhibit food intake via activation of the receptors on afferent (mostly vagal) nerves stimulating the satiety center and inhibiting the feeding center (9) ( Fig
These findings underscore the developmental importance of early microbial signals in shaping neural circuits and behavior, processes modulated by molecules such as reelin, which controls dendritic growth and synaptic receptor function in post-natal entorhinal cortex neurons (Hamad et al., 2021b,a, 2024b,a