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Nucleosomal Histone Peptides Endogenous peptide epitopes of histones from nucleosomes induce immune tolerance and promote CD4 + and CD8 + T reg responses, and reduce lupus nephritis and B cell activation in (SWR x NZB) F1 (SNF1) mice, [70, 71, 72] also blocking pathogenic autoimmunity in human SLE

Auerdem kann es helfen, Muskelmasse zu erhalten, was besonders bei lteren Erwachsenen und Menschen in Rehabilitationsphasen nach Verletzungen ntzlich ist

Ericsen BO, Mathisen UD, Melson T, Ingebretsen OC, Jenssen TG, Njolstad I, et al

These are some examples of how OoC technology can represent a next-generation preclinical testing tool, moving beyond conventional toxicology toward precision immuno-oncology, where patient-derived chips could guide therapeutic decisions and dose optimization while reducing reliance on animal models