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Invega Sustenna/Xeplion/Invega Trinza/Trevicta (paliperidone) Disease area(s): Psychiatry Manufacturer(s): Johnson & Johnson 2024 Sales (USD): $4.22 billion Why it sold so well: In 2024, J&Js long-acting antipsychotic portfolio including Invega Sustenna, Xeplion, Invega Trinza and Trevicta registered global sales of $4.22 billion, reflecting a 2.6% year-over-year increase

The decreased regeneration capacity of muscles is due to both extrinsic (low amino acid intake and lack of muscle stimulation due to low physical activity) and intrinsic factors (blunted protein synthesis responses, and increased circulation of inflammatory and catabolic cytokines) [36]

US Renal Data System 2016 Annual Data Report: Epidemiology of Kidney Disease in the United States

While that may seem straightforward, peptides encompass thousands of compounds with vastly different functions