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Compared with the normal feeding model, the kidney inflammation genes such as Emr1, Nos2, and Tnfa were downregulated, and the degree of basophil aggregation was lower in the MR model

, Long-term Safety and Efficacy of Achieving Very Low Levels of Low-Density Lipoprotein Cholesterol : A Prespecified Analysis of the IMPROVE-IT Trial, JAMA Cardiol

Lipids 1862, 14041413

The healing mechanisms examined include stimulation of granulation tissue formation, increased mucosal prostaglandin E2 production (critical for mucosal defence), restoration of mucus layer integrity, and promotion of mucosal blood flow through NO synthesis