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After GLP-1 binding to GLP-1R, this complex could upregulate cAMP thereby activating the PKA/CREB pathway [24]

GLP-1 receptor agonists are medications that mimic the action of the hormone glucagon-like peptide-1, enhancing insulin secretion, inhibiting glucagon release, slowing gastric emptying, and promoting satiety

Interestingly, the tested GLP-1 agonists outperformed the traditional AUD medications in reducing AUD-related hospitalization risks, highlighting their potential as a novel treatment approach