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The stroke is invariably accompanied by the breach of the blood-brain barrier and infiltration of blood-borne elements into the brain parenchyma

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Keap1 contains two known protein-interacting domains: the BTB (bric-a-brac, tramtrack, broad-complex) domain in the N terminal region and the Kelch repeats in the C terminal region homologous to Drosophila actin-binding protein Kelch [Kelch repeat, double glycine repeat (DGR) domain] ( Figure 2 a )

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