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How Vitamin B12 Affects Brain Chemistry and Stress Systems Neurotransmitter production B12, together with folate and B6, is essential for the methylation reactions that produce serotonin, dopamine, norepinephrine, and GABA the neurotransmitters most directly involved in regulating mood, motivation, calm, and emotional stability

that compliance and monitoring are better in patients who receive this form of therapy because they have frequent contact with health care providers, whereas proponents of oral therapy maintain that compliance will be improved in patients who receive oral therapy because of convenience, comfort, and decreased expense

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