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To assess the associations of semaglutide with recurrent CUD, the study population included 2034 patients who had active medical encounters for the diagnosis of obesity in 6/202112/2022, were for the first time (new users design) prescribed semaglutide or non-GLP-1RA anti-obesity medications during 6/202112/2022 (time zero or index event), had a diagnosis of CUD on or before the index event, and had a diagnosis of at least one of obesity-associated comorbidities on or before the index event

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Therefore, GLP-1 is save for use in T2DM and non-diabetic patients (97)

To qualify, beneficiaries need to meet one of three BMI-based pathways (BMI 35 alone