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Though exact dosing for retatrutide in the weight-loss setting is still being defined (because many of the uses remain investigational), in the key trial adults with obesity treated weekly showed large body weight reductions: e.g., up to ~17.5% at 24 weeks and up to ~24% at 48 weeks in certain dose groups

The American Diabetes Association recommends that all patients receive initial injection training from a healthcare professional and periodic technique review to maintain proper administration skills

Trying smaller, more frequent meals

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