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In preclinical studies, compounds such as VX-765 and pralnacasan have demonstrated efficacy in inhibiting caspase-1 activation and protecting against inflammatory diseases

Six studies have evaluated the effects of the mimetics, exenatide (86, 108, 109, 134) or liraglutide (79, 109)

Figure 4 It is thought that many chronic illnesses, including ME/CFS, originate with reactivation of latent or dormant viruses that are present in the body, caused by a change in physiological conditions (127)

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