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It is relevant to note that, in patients with upper gastrointestinal symptoms, there are about 25% of patients with delayed gastric emptying, about 25% with impaired gastric accommodation, and about 25% with the combination of both gastric motor dysfunctions (Park et al., 2017

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Moreover, increased plasma insulin levels also increase the amount of circulating free androgens by reducing the production of Sex Hormone-Binding Globulin (SHBG) in the liver [15]

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