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The lack of affordable, accessible GLP-1 medications will continue to obfuscate future large cohort analysis of patients using them due to the disrupting influences of social determinants of health

In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)

What it is claimed to do: Accelerate wound healing and tissue repair Promote new blood vessel formation (angiogenesis) Reduce inflammation Support tendon, ligament, and muscle recovery What the research shows: A study published in the Journal of Physiology and Pharmacology (Sikiric et al., 1997) found that BPC-157 promoted healing in rat models by enhancing granulation tissue formation, angiogenesis, and collagen production

While erastin (an inhibitor of the cystineglutamate antiporter system Xc) was senolytic in SK-MEL-103 cells and BSO (a sulfoximine derivative that reduces levels of glutathione) in IMR90 cells, only the three GPX4 inhibitors tested showed senolytic activity in all senescent models tested (Extended Data Fig