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In addition, the Glu74 and Glu83 residues of ChaC2 are key for directing the conformation of the enzyme and regulating enzyme activity (20)

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To determine whether PQQ-induced cell apoptosis was associated with oxidative stress levels in chondrosarcoma SW1353 cells, DCFH-DA staining and flow cytometry were used to detect the changes in the levels of ROS and hydroxyl radicals in SW1353 cells treated with 120 M PQQ for 24 h

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