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The mechanism of action for Ozempic is multifaceted: Slowing Gastric Emptying: One of its primary effects is to slow down the rate at which food leaves the stomach

Novo Nordisk has also cited indirect comparison data suggesting that fewer patients discontinued oral semaglutide due to side effects compared with orforglipron, though the companies and independent commentators note the significant methodological limitations of such comparisons in the absence of a head-to-head obesity trial

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