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This theoretically preserves the cytosolic pool of NAD+ (Nicotinamide Adenine Dinucleotide), which is critical for sirtuin activation and mitochondrial oxidative phosphorylation

Research Caveats & Emerging Approach While each therapy has strong research support on its own, studies combining TRT + GLP-1 are still emerging

Hormone therapies and GLP-1 treatments work well together for many patients, helping them achieve a healthy weight and body composition while increasing energy, restoring fertility, supporting sleep, enhancing drive, and more

One of the issues about being on GLP-1 medication is that your thirst and your hunger drives are significantly decreased, said Sowa, adding that the flavors are formulated to be easier on a GLP-1 users taste buds