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Because these are time-dependent events, it is critical to always assess multiple time points in a pathophysiology and use parameters specific for apoptosis, while keeping in mind that many apoptosis parameters can also be modulated during a necrotic cell death

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Serine is critical for cancer progression, fueling macromolecule synthesis (proteins, lipids, nucleotides), antioxidant defense (glutathione production), and one-carbon metabolism (methylation, tRNA formylation) [13]