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Following menthol administration, male rats self-administered more intravenous nicotine infusions and increased their motivation to obtain nicotine (151), and male mice self-administered electronic cigarette vapor containing menthol and nicotine at greater levels than nicotine vapor alone (61)

Archived from the original (PDF) on March 4, 2016

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The researchers wanted to know whether prolonged use of a device, with more puffs and more heating cycles, would cause these compounds to accumulate in the remaining fluid over time