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We assumed this younger cohort is 80% female, consistent with modeling from the Institute for Clinical and Economic Review (ICER) in its 2022 report estimating an annual VBP of $9,700

It was approved in 2010 to reduce abdominal fat accumulation seen in HIV patients diagnosed with lipodystrophy, a condition of fatty accumulation around the abdomen

Plan sponsors should get ahead of this trend by proactively evaluating how DTC models could impact their drug spend and explore options that maintain prescription affordability and access

Its mechanism involves appetite regulation, increased energy utilization, and enhanced insulin sensitivity, demonstrating greater efficacy than current monotherapies (Tschp et al., 2023)